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1、一38一介入放射學(xué)雜志2014年1月第23卷第1期JInterventRadiol2014,V0l-23,N0.1·非血管介入Non.vascularintervention·經(jīng)皮肝穿刺微波治療肝癌的嚴(yán)重并發(fā)癥18例分析胡清雯,錢國軍【摘要】目的分析經(jīng)皮肝穿刺微波熱凝毀損肝癌治療的嚴(yán)重并發(fā)癥及其預(yù)防和治療措施。方法2010年1月一2011年12月,對經(jīng)臨床或病理證實為原發(fā)或轉(zhuǎn)移性肝癌的患者共進(jìn)行了3419例次經(jīng)皮肝穿刺微波術(shù)治療肝癌。所有患者術(shù)后均定期隨訪,了解與手術(shù)相關(guān)的近期及遠(yuǎn)期并發(fā)癥的發(fā)生與愈后。結(jié)果共發(fā)生嚴(yán)重并發(fā)癥18例,包括腹腔出血1例,腸瘺1例,膽道損傷3例,急性腎衰竭1
2、例,感染12例。其中因并發(fā)癥死亡3例。嚴(yán)重并發(fā)癥發(fā)生率0.53%(18/3419),并發(fā)癥相關(guān)病死率16.7%(3/18)。結(jié)論經(jīng)皮肝穿刺微波熱凝毀損肝癌治療術(shù)對于肝腫瘤部位相對復(fù)雜或特殊、凝血機(jī)制及全身情況較差者,仍存在有較大的風(fēng)險。須嚴(yán)格掌握適應(yīng)證,術(shù)前應(yīng)有針對性的對癥治療及術(shù)前準(zhǔn)備,術(shù)中規(guī)范及精準(zhǔn)的經(jīng)皮肝穿刺操作,術(shù)后嚴(yán)密觀察病情變化,其中有些并發(fā)癥可以防治,有些可以及早發(fā)現(xiàn)并獲得積極救治,減少并發(fā)癥所導(dǎo)致的相關(guān)病死率及其不良影響【關(guān)鍵詞】肝癌;微波;并發(fā)癥中圖分類號:R735.7文獻(xiàn)標(biāo)志碼:A文章編號:1008—794X(2014)一01.0o38.04Severecompl
3、icationsofpercutaneousmicrowavecoagulationtherapyforhepaticmalignancy:ananalysisof18casesHUQing-wen,QIANGuo—jun.DepartmentofMinimalInvasionTherapy,theAfiliatedEasternHepatobiliralySurgeryHospital,theSecondMilitaryMedicalUniversity,Shanghai2oo438.ChinaCorrespondingauthor:QIANGuo-jun,E—mail:q@sin
4、a.com【Abstract】ObjectiveToanalyzethecause,preventionandtreatmentofseverecomplicationsofpercutaneousmicrowavecoagulationtherapy(PMCT)forhepaticmalignancy.MethodsDuringtheperiodfromJan.2010toDec.2011.a(chǎn)totalof3419proceduresofPMCTwerecarriedoutinauthors’hospitalforpatientswithpathologically—orclini
5、cally—confirmedhepaticcarcinomaorhepaticmetastasis.Allthepatientswereperiodically~llowedup.Theprocedure·relatedandshort—to—long—termcomplicationswererecorded.Theresultswereanalyzed.ResultsSeverecomplicationsoccurredin18patients,whichincludedintra—abdominalhemorhage(n=1),bowelleakage(n=1),biledu
6、ctinjury(n=3),acuterenalfailure(n=1)andinfection(n=12).Threepatientsdiedofaboveseverecomplications.Theincidenceofcomplicationwas0.53%(18/3419)andthecomplication—relatedmortalitywas16.67%(3/18).ConclusionAlthoughPMCTisaminimallyinvasivetechnique,itstillcarriesrisksforpatientswithinsuficientblood
7、coagulationandpoorclinicalconditionorforpatientswiththetumorbeinglocatedattheunusualregions.Theindicationsshouldbestrictlyobserved.Carefulperioperativepreventionmeasures,closeobservationafterthetreatmentandearlydetectionofcomplica