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1、急診PCI治療老年急性心肌梗死的臨床療效觀察作者:凌瑋,王志,楊華志,王秀芝,楊波,王東方【關(guān)鍵詞】,急性心肌梗死;,,血管成形術(shù),經(jīng)腔,經(jīng)皮冠狀動(dòng)脈;,,老年人摘要:目的:觀察和評價(jià)急診冠狀動(dòng)脈介入治療(PCI)治療老年急性心肌梗死(AMI)的療效和安全性。方法:回顧性分析2004年7月至2006年7月因急性心肌梗死實(shí)行急診PCI(W12h)的患者61例,其屮$60歲的30例(老年組),V60歲的31例(中輕組),分析兩組基礎(chǔ)資料特征,即刻手術(shù)成功率和隨訪期間主要不良心血管事件(復(fù)發(fā)性心絞痛、心肌梗死及猝死)發(fā)生率的差異。結(jié)果:老年
2、組心力衰竭及多支病變比例高于中輕組(分別為40%,6%和52%,23%,P均V0.05),老年組入院至梗死相關(guān)動(dòng)脈開通時(shí)間長于中輕組[(63.86土16.7)min(51.16±13.5)min,P<0.05]o兩組患者急診PCI成功率分別為老年組97%,中輕組100%,兩組無顯著差異(P>0.05)o住院期間死亡老年組3例,中輕組0例,兩組亦無顯著差異(P>0.05)o隨訪4個(gè)月至2年,老年組發(fā)生心絞痛6例、心肌梗死3例、猝死0例(共占30%);中輕組發(fā)生心絞痛2例、心肌梗死1例、猝死0例(總計(jì)10%),隨訪期間主要不良
3、心血管事件發(fā)生率兩組有顯著性差異(P<0.05)o結(jié)論:急診PCT成功率和住院期間死亡率老年組和中輕組無顯著差異,雖然老年組心血管不良事件發(fā)生率高于中輕組,但仍證明急診PCI對老年AMI患者梗死動(dòng)脈的開通是安全有效的并有良好的近、中期預(yù)后。關(guān)鍵詞:急性心肌梗死;血管成形術(shù),經(jīng)腔,經(jīng)皮冠狀動(dòng)脈;老年人ObservetheeffectofPrimaryPercutaneousCoronaryInterventioninPatientswithAcuteMyocardialInfarctioninAgedAbstractObjectiveT
4、oobserveandassessthesafetyandefficacyofrecentandmid-termoutcomeofprimarypercutaneouscoronaryintervention(PCI)inpatientswithacutemyocardialinfarction(AMI).Method:12h)underwentprimaryPCIandweredividedintotheeldergroup(260ys,n=30)andtheyoungergroup(<60ys,n=31)?Thebasicchar
5、acteristies,immediatesuccessrateandmajoradversecardiacevents(MACE)asrecurrentangina,myocardialinfarctionandsuddencardiacdeathduringfol1ow-upwereanalyzedbetweentwogroups.Result:TheratioofpatientswithheartfailureandmuIti-vessellesionswashigherintheeldergroupthanthatinthey
6、oungergroup(40%vs6%and52%vs23%,respectively,P<0.05)?Timefromadimissiontorevacularizationofinfarctionrelatedartery(IRA)waslongerintheeldergroupthanthatintheyoungergroup[(63.86土16.7)minvs(51.16土13.5)min,P<0.05]?TheimmediatesuccessrateofprimaryPCIwere97%andl00%ineldergroup
7、andyoungergrouprespectively.3patientsdiedintheeldergroupandnoneintheyoungergroup(P>0.05).Duringthefollow-upperiod,6recurrentangina,3AMIandnosuddencardiacdeathwerereportedintheeldergroupwhereasintheyoungergrouponly2recurrentangina,oneMIandnosuddencardiacdeathwererepor
8、ted?TheMACEratiowas30%andlO%intheelderandyoungergrouprespectively(P<0.05)?Conelusion:Theimmediatesuccessrateof