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1、顯微手術(shù)配合伽瑪?shù)吨委煷笮吐犐窠?jīng)瘤祁紅(徐州醫(yī)科大學(xué)第二附屬醫(yī)院放療科江蘇徐州221006)【摘要】目的:探討分析使用顯微手術(shù)配合伽瑪?shù)吨委煷笮吐牭r經(jīng)瘤的臨床效果。方法:選取木院2014年12月?2015年12月期間確診的大型聽神經(jīng)瘤患者21例,征得患者及家屬同意,分為觀察組12例,采用顯微手術(shù)配合伽瑪?shù)吨委煷笮吐牭r經(jīng)瘤,對照組9例,僅采用單純顯微手術(shù)治療聽祌經(jīng)瘤,觀察比較兩組的治療效果及并發(fā)癥。結(jié)果:治療后12個月隨訪結(jié)果發(fā)現(xiàn),經(jīng)顯微手術(shù)配合伽瑪?shù)吨委煹挠^察組,面神經(jīng)功能優(yōu)良者有9人,占75.0%,面神經(jīng)功能差者有3人,占25.0%,僅經(jīng)顯微手
2、術(shù)治療的對照組面祌經(jīng)功能優(yōu)良者有5人,占55.6%,面神經(jīng)功能差者有4人,占44.4%,兩組比較,P〉0.05,差異顯著,兩組術(shù)手并發(fā)癥比較,觀察組患者有2例出現(xiàn)腦積水,后經(jīng)引流后治愈,對照組患者有2例腦積水,后經(jīng)治療后治愈。兩組患者均無顱內(nèi)祌經(jīng)損傷等明顯并發(fā)癥。12個月隨訪結(jié)果發(fā)現(xiàn),經(jīng)顯微手術(shù)配合伽瑪?shù)吨委煹挠^察組腫瘤全部消失有9例(75%),瘤體縮小的有2例(17%),無變化的有1例(8%);對照組患者中腫瘤全部消失的有5例(56%),瘤體縮小的有1例(11%),無變化的有2例(22%),瘤體略增大的有1例(11%)。觀察組術(shù)后并發(fā)癥較對照組
3、要低,兩組比較,P〉0.05,差異顯著。結(jié)論:顯微手術(shù)配合伽瑪?shù)吨委煷笮吐犐窠?jīng)瘤臨床效果顯著,可以提高患者生存質(zhì)量,具有較高應(yīng)用價值?!娟P(guān)鍵詞】顯微鏡;伽瑪?shù)?;大型聽祌經(jīng)瘤;臨床療效【中圖分類號】R730.5【文獻(xiàn)標(biāo)識碼】A【文章編號】1007-8231(2016)02-0123-02Microsurgerywithgammaknifetreatmentoflargeacousticneuroma【Abstract】ObjectiveTostudytheanalysisoftheuseoflargeacousticneuromamicrosurg
4、erywithgammaknifetreatmentofclinicaleffect.MethodsOurhospitalduringtheperiodofDecember2014?December2015confirmed21patientswithlargeacousticneuroma,consentofthepatientandfamily,dividedintoobservationgroupandcontrolgroup,12caseswithlargeacousticneuromamicrosurgerywithgammaknife
5、treatment,controlgroup,9caseswithacousticneuromamicrosurgerytreatmentalone,onlyobservethecomparisonoftwogroupsoftherapeuticeffectandcomplications.Results12monthsfollow-upaftertreatmentresultsshowthattheobservationofmicrosurgerywithgammaknifetreatmentgroup,excellentfacialnerve
6、functionofninepeople,accountingfor75.0%,facialnervefunctionmemory,thereare3people,accountingfor25.0%,themicrosurgerytreatmentofthecontrolgrouponlyexcellentfacialnervefunctionhasfivepeople,accountingfor55.6%,facialnervefunctionclaimhasfourpeople,accountingfor44.4%,comparedtwog
7、roups,P>0.05,significantdifference,handcomplicationscomparedthetwogroups,observationgroupofpatientswithhydrocephalusin2cases,aftercuredbydrainageafter,in2casesofcontrolgroupinpatientswithhydrocephalus,aftercuredaftertreatment.Twogroupsofpatientshadnoobviouscomplicationsuch
8、ascranialnerveinjury.12monthsfollow-upresultsshowthattheobservationg