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1、攬香烯注射液在子宮切口妊娠介入治療中的應用上海中醫(yī)藥大學附屬曙光醫(yī)院200021【摘要】目的:探討欖香烯注射液經(jīng)子宮動脈灌注結(jié)合動脈栓塞,治療切口妊娠的臨床價值。方法:14例切U妊娠住院患者,入院1-3天內(nèi)行雙側(cè)子宮動脈灌注栓塞介入治療。隨機分為欖香烯組7例,經(jīng)子宮動脈灌注欖香烯20-40ml;甲氨蝶呤組7例,經(jīng)子宮動脈灌注甲氨蝶呤50-100mg;雙側(cè)子宮動脈以明膠海綿粉/碎粒、明膠海綿條栓塞。結(jié)果:介入術(shù)后兩組患者均未岀現(xiàn)子宮破裂大岀血。術(shù)后3天內(nèi)觀察血HCG變化。欖香烯組HCG下降〉50%6例,
2、<50%1例;甲氨蝶呤組HCG下降〉50%4例,<50%3例。結(jié)論:欖香烯區(qū)域灌注結(jié)合子宮動脈栓塞治療切U妊娠療效確切,欖香烯是中藥莪術(shù)的提取物,有行氣破血抗早孕的功效??赡茉谝种婆咛ゼ毎敝车耐瑫r,還促進局部血栓的形成,促使孕囊缺血、壞死。【關(guān)鍵詞】子宮切U妊娠,欖香烯,區(qū)域灌注,動脈栓塞TheapplicationofElemeneinjectionintheinterventionaltreatmentforuterineincisionalpregnancyShanghaiShuguangho
3、spitalaffiliatedwithShanghaiUniversityofT.C.M.200021DepartmentofradiologyGenJian,YaoMing-rong,HuangXue-jing,LuMeng-ying,ZhangAn-junAbstract:Objective:Todiscusstheclinicalvalueofintra-arterialElemeneinjectioninfusion,combinedwitharterialembolization.Meth
4、od:Atotalof14patientswithuterineincisionalpregnancy,whoreceivedintra-arterialinfusioncombinedwitharterialembolizationwithin1雜3daysofadmission,werestudied.Theywererandomlyassignedintotwogroups:patientsingroupElemene(n=7)receivedintra-arterialinfusionofEl
5、emeneinjection(20-40ml).PatientsingroupMethotrexate(MTX,n=7)receivedintra-arterialinfusionofMethotrexate(50-100mg).Bilateraluterinearterialembolizationwasperformedwithgelfoamparticlesorgelfoamsponge.Result:Neithergroupexperiencedruptureofuterusaftertrea
6、tment.ThechangeofB-HCGwasobservedwithin3daysofoperation.AmongtheElemenegroup,6patientsexhibitedadecreaseinHCG>50%,and1exhibitedadecrease<50%;amongtheMTXgroup4patientsexhibitedadecrease>50%,and3exhibitedadecrease<50%.Conclusion:Themethodofint
7、ra-arterialElemeneinjectioninfusioncombinedwitharterialembolizationinincisionalpregnancyiseffective.ElemeneisanextractofRhizomaZedoariae.IthasaneffectofacceleratingQlandbloodcirculationwhichcouldpromotetheterminationofearlypregnancy.Itmayinhibittherepro
8、ductionofembryoniccell,whileencouragingtheformationofthrombosis,causingischemicnecrosisinthegestationalsac.Keywords:Incisionalpregnancy,elemene,intra-arterialinfusion,arterialembolization子宮切u妊娠是一種比較少見的異位妊娠,如果處理不當,會造成子宮破裂、大出血而危及生命